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Tony Wyss-Coray

Tony Wyss-Coray is a neuroscientist at Stanford University.[12]He specializes in neurological sciences.[13]

Tony Wyss-Coray is a researcher at Stanford where he is seeking that elusive Fountain of Youth.[4]“Age is the major risk factor for many of the leading causes of death in the world, including heart disease, cancer, stroke, and dementia,” reads Alkahest’s website, a private company co-founded by Wyss-Coray.[5]In his work, the protein is twice as concentrated in cord plasma as in young blood, and its levels remain constant in later life.[6]In 2014, the prestigious US journal, Science, named his work on young blood one of its breakthroughs of the year.[7]

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Stanford University

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Protein in umbilical cord blood may restore the aging brain

Moreover, as the biological and behavioral characteristics of mice closely resemble those of humans, the discovery increases the likelihood that younger plasma would benefit older people's cognitive ability. Specifically, the team pinpointed a protein in the umbilical cord plasma - which is abundant in human umbilical cord blood but decreases with age - that was capable of mimicking the rejuvenating effect on old mice's brain function without the need to inject the rest of the plasma. Wyss-Coray, Castellano, and colleagues compared umbilical cords, blood plasma from 19- to 24-year olds, and blood plasma from 61- to 82-year olds in order to identify changes that are associated with age in a number of proteins. The researchers suspected that these age-associated changes might have an effect on the hippocampus, the brain structure critical for "converting experiences into long-term memories" in both humans and mice. The researchers tested the effect of old and young human blood, as well as the most youthful human blood of all - umbilical cord blood - on the hippocampal function of mice.[8]

2017-04-20

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