Katherine L. Nathanson

Katherine L. Nathanson is affiliated with the University of Pennsylvania.[1]She specializes in genetics.[2]

Nathanson is a professor of Translational Medicine and Human Genetics in the Perelman School of Medicine, and the associate director for Population Sciences in the Abramson Cancer Center, co-leader of the Cancer Control Program, and Chief Oncogenomics Physician.[3]She also serves as director of Genetics for the Basser Center for BRCA.[3]She received her bachelors degree from Haverford College and her MD from the University of Pennsylvania.[3]In addition, she is the chair of the cancer genetics section for the National Institutes of Health and acts as the editor of cancer genetics for the Genetics in Medicine journal.[4]Her group evaluated the genetic profiles of 160 breast and ovarian cancers associated with germline mutations in BRCA1 and BRCA2, in the largest study of these tumors to date.[5]Her research focuses on inherited and somatic genetic/genomic changes in cancer and how discoveries in this area can be applied to improve patient care.[6]

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Abramson Cancer Center


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Recent events

Penn Med prof. Katherine Nathanson receives $3 million grant for cancer research

Katherine Nathanson, deputy director of Penn's Abramson Cancer Center, has received a $3 million grant to study how BRCA genes affect immune function, the Almanac reported. Nathanson's research looks at BRCA gene mutations, or specific genetic changes associated with increased rates of breast, ovarian, prostate, and pancreatic cancer. In 2012, the Grays donated $30 million to establish the Basser Center for BRCA at the Abramson Cancer Center, named for Mindy Gray's sister Faith Basser who passed away from a BRCA-related ovarian cancer.[7]


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Deputy Director of Penn's Abramson Cancer Center Receives $3 Million Grant from The Gray Foundation

Katherine L. Nathanson, MD, deputy director of the Abramson Cancer Center at the University of Pennsylvania and the Pearl Basser Professor for BRCA-Related Research in Penn’s Perelman School of Medicine, has been awarded a $3 million research grant from the Gray Foundation. This new Team Science Grant, titled the "Determinants of immune activity and molecular features in BRCA1/2 mutation carriers," will support Nathanson and her team as they study new approaches to understanding immune function both in healthy BRCA mutation carriers and BRCA-related cancers.[8]


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University of Pennsylvania: Basser Center Takes Aim at BRCA

Twenty-five years after the discovery of genetic mutations that dramatically increase cancer risk, Penn Medicine's Basser Center for BRCA is building scientific knowledge alongside public awareness about BRCA-related cancers. An expert on cancer genetics, Katherine Nathanson, director of genetics for the Basser Center, has also seen the growing role of immunology in cancer science during her years at Penn. Efforts by Domchek and others in the Basser Center have led to new paradigms for treatment of BRCA-related cancers.[9]


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