He is renowned for his transformative studies examining the molecular mechanisms of insulin resistance in humans, and his work has been vastly important to our knowledge of the origination and development of type 2 diabetes.He is also the Co-Director of the Yale Diabetes Research Center.Following an internship and residency at Duke University Medical Center, he did an endocrinology fellowship and the Massachusetts General Hospital-Harvard Medical School.Dr. Shulman has pioneered the use of magnetic resonance spectroscopy to non-invasively examine intracellular glucose and fat metabolism in humans that have led to several paradigm shifts in our understanding of type 2 diabetes.Dr. Shulman is a Fellow of the American Association for the Advancement of Science and he has been elected to the American Society for Clinical Investigation, the Association of American Physicians, The Institute of Medicine and the National Academy of Sciences.In 2006, he created the Newcastle Magnetic Resonance Centre and has focussed on developing techniques to elucidate how food is handled by the body in health and disease.
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Very low calorie diets could potentially reverse diabetes, indicates new study. To determine that diets could reverse diabetes, they gave the animals one-quarter of their typical dietary intake and studied how their bodies reacted, particularly to insulin resistance and glucose, or sugar, production by the liver, as these two functions can lead to increased blood-sugar levels in diabetics. "Using this approach to comprehensively interrogate liver carbohydrate and fat metabolism, we showed that it is a combination of three mechanisms that is responsible for the rapid reversal of hyperglycemia following a very low-calorie diet," senior author Gerald I. Shulman, M.D., said in a statement. Next up is a study in patients who have Type 2 diabetes and are undergoing bariatric surgery or are on very low-calorie diets.